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This research programme did not identify quantifiable benefits to annual monitoring of chronic kidney disease, but new approaches to monitoring chronic heart failure show promise if high within-test variability can be overcome.

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Rafael Perera 1,*, Richard Stevens 1, Jeffrey K Aronson 1, Amitava Banerjee 2, Julie Evans 1, Benjamin G Feakins 1, Susannah Fleming 1, Paul Glasziou 3, Carl Heneghan 1, FD Richard Hobbs 1, Louise Jones 1, Milena Kurtinecz 1, Daniel S Lasserson 4, Louise Locock 5, Julie McLellan 1, Borislava Mihaylova 6,7, Christopher A O’Callaghan 8, Jason L Oke 1, Nicola Pidduck 1, Annette Plüddemann 1, Nia Roberts 9, Iryna Schlackow 6, Brian Shine 10, Claire L Simons 6, Clare J Taylor 1, Kathryn S Taylor 1, Jan Y Verbakel 1,11,12, Clare Bankhead 1

1 Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
2 Institute of Health Informatics, University College London, London, UK
3 Institute for Evidence-Based Healthcare, Faculty of Health Sciences & Medicine, Bond University, Gold Coast, QLD, Australia
4 Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
5 Health Services Research Unit, University of Aberdeen, Aberdeen, UK
6 Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
7 Institute of Population Health Sciences, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK
8 Nuffield Department of Medicine, University of Oxford, Oxford, UK
9 Bodleian Health Care Libraries, Knowledge Centre, University of Oxford, Oxford, UK
10 Department of Clinical Biochemistry, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
11 Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium
12 National Institute for Health Research (NIHR) Community Healthcare MedTech and In Vitro Diagnostics Co-operative (MIC), Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
* Corresponding author Email:

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