Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and Pseudomonas aeruginosa infection: the TORPEDO-CF RCT

Langton Hewer, Simon C; Smyth, Alan R; Brown, Michaela; Jones, Ashley P; Hickey, Helen; Kenna, Dervla; Ashby, Deborah; Thompson, Alexander; Sutton, Laura; Clayton, Dannii; Arch, Barbara; Tanajewski, Łukasz; Berdunov, Vladislav; Williamson, Paula R

doi:10.3310/hta25650

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Intravenous antibiotics were not more likely than oral antibiotics to achieve eradication of Pseudomonas aeruginosa infection at 3 months and patients remaining infection-free at 15 months.

Simon C Langton Hewer , Alan R Smyth , Michaela Brown , Ashley P Jones, Helen Hickey , Dervla Kenna , Deborah Ashby , Alexander Thompson , Laura Sutton , Dannii Clayton , Barbara Arch , Łukasz Tanajewski , Vladislav Berdunov & Paula R Williamson .

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Simon C Langton Hewer ^1,^2,^*,^†, Alan R Smyth ^3,^†, Michaela Brown ⁴, Ashley P Jones ⁴, Helen Hickey ⁴, Dervla Kenna ⁵, Deborah Ashby ⁶, Alexander Thompson ⁷, Laura Sutton ⁴, Dannii Clayton ⁴, Barbara Arch ⁴, Łukasz Tanajewski ⁸, Vladislav Berdunov ⁸, Paula R Williamson ⁴

¹ Department of Paediatric Respiratory Medicine, Bristol Royal Hospital for Children, ,
² University of Bristol, Bristol, UK
³ Division of Child Health, Obstetrics and Gynaecology, University of Nottingham, Nottingham, UK
⁴ Liverpool Clinical Trials Centre, University of Liverpool, a member of the Liverpool Health Partners, Liverpool, UK
⁵ Antimicrobial Resistance and Healthcare Associated Infections Reference Unit, National Infection Service, Public Health England, London, UK
⁶ School of Public Health, Imperial College London, London, UK
⁷ Manchester Centre for Health Economics, The University of Manchester, Manchester, UK
⁸ Division of Pharmacy Practice and Policy, School of Pharmacy, University of Nottingham, Nottingham, UK
^* Corresponding author Email: simon.langtonhewer@bristol.ac.uk

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Response by Dr Lukasz Tanajewski on 26 November 2021 at 1:02 PM
Author affiliation correction

The correct author affiliation: Lukasz Tanajewski, Department of Economics, Kozminski University, Warsaw, Poland and Division of Pharmacy Practice and Policy, School of Pharmacy, University of Nottingham, Nottingham, UK

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