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This trial found that in delivering cancer chemotherapy, centrally inserted totally implantable venous access devices had lower complication rates than centrally inserted tunnelled catheters, and lower rates than peripherally inserted central catheters.

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Olivia Wu 1,*, Elaine McCartney 2, Robert Heggie 1, Evi Germeni 1, James Paul 2, Eileen Soulis 2, Susan Dillon 2, Caoimhe Ryan 3, Moira Sim 1, Judith Dixon-Hughes 2, Roshan Agarwal 4, Andrew Bodenham 5, Tobias Menne 6, Brian Jones 7, Jonathan Moss 8

1 Health Economics and Health Technology Assessment (HEHTA), Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
2 Cancer Research UK Glasgow Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK
3 School of Social Sciences, University of Dundee, Dundee, UK
4 Oncology, Northampton General Hospital, Northampton, UK
5 Intensive Care, Leeds Teaching Hospitals, Leeds, UK
6 Haematology, Newcastle Freeman Hospital, Newcastle upon Tyne, UK
7 Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK
8 Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
* Corresponding author Email:

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