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Interpretation of the results is limited owing to earlier than anticipated termination of the study, meaning that the numbers available for analysis are small, but the overall success rate was low.

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David G Jayne 1,*, Annabelle E Williams 2, Neil Corrigan 3, Julie Croft 3, Alison Pullan 3, Vicky Napp 3, Rachel Kelly 3, David Meads 4, Armando Vargas-Palacios 4, Adam Martin 4, Claire Hulme 5, Steven R Brown 6, Karen Nugent 7, Jen Lodge 8, David Protheroe 9, Sushil Maslekar 10, Andrew Clarke 11, Pasha Nisar 12, Julia M Brown 3

1 Academic Surgery, Leeds Institute of Medical Research at St James’s, University of Leeds, Leeds, UK
2 Colorectal and General Surgery, Milton Keynes University Hospital, Milton Keynes, UK
3 Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK
4 Academic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK
5 Health Economics Group, Institute of Health Research, University of Exeter Medical School, Exeter, UK
6 Department of Colorectal Surgery, Northern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
7 University of Southampton, Southampton, UK
8 Bowel Health and Pelvic Floor Dysfunction Community Urology and Colorectal Service (CUCS), Leeds Community Healthcare NHS Trust, Leeds, UK
9 Department of Liaison Psychiatry, Leeds General Infirmary, Leeds and York Partnership NHS Foundation Trust, Leeds, UK
10 St James’s Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK
11 Poole Hospital NHS Foundation Trust, Poole, UK
12 St Peter’s Hospital, Ashford and St Peter’s Hospitals NHS Foundation Trust, Chertsey, UK
* Corresponding author Email:

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