Switching antipsychotic medication to reduce sexual dysfunction in people with psychosis: the REMEDY RCT

Crawford, Michael J; Thana, Lavanya; Evans, Rachel; Carne, Alexandra; O’Connell, Lesley; Claringbold, Amy; Saravanamuthu, Arunan; Case, Rebecca; Munjiza, Jasna; Jayacodi, Sandra; Reilly, Joseph G; Hughes, Elizabeth; Hoare, Zoe; Barrett, Barbara; Leeson, Verity C; Paton, Carol; Keown, Patrick; Pappa, Sofia; Green, Charlotte; Barnes, Thomas RE

doi:10.3310/hta24440

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Reluctance of staff to discuss sexual side effects and patient concerns about switching medication led to low recruitment and the trial being stopped after an extended pilot phase.

Michael J Crawford , Lavanya Thana , Rachel Evans , Alexandra Carne , Lesley O’Connell , Amy Claringbold , Arunan Saravanamuthu , Rebecca Case , Jasna Munjiza , Sandra Jayacodi , Joseph G Reilly , Elizabeth Hughes , Zoe Hoare , Barbara Barrett , Verity C Leeson , Carol Paton , Patrick Keown , Sofia Pappa , Charlotte Green & Thomas RE Barnes .

Detailed Author information
Detailed Author information

Michael J Crawford ^1,^*, Lavanya Thana ¹, Rachel Evans ², Alexandra Carne ³, Lesley O’Connell ¹, Amy Claringbold ¹, Arunan Saravanamuthu ⁴, Rebecca Case ⁴, Jasna Munjiza ^1,⁴, Sandra Jayacodi ⁴, Joseph G Reilly ³, Elizabeth Hughes ⁵, Zoe Hoare ², Barbara Barrett ⁶, Verity C Leeson ¹, Carol Paton ⁷, Patrick Keown ⁸, Sofia Pappa ^1,⁹, Charlotte Green ⁴, Thomas RE Barnes ¹

¹ Division of Psychiatry, Imperial College London, London, UK
² North Wales Organisation for Randomised Trials in Health and Social Care, University of Bangor, Bangor, UK
³ Tees, Esk and Wear Valleys NHS Foundation Trust, Darlington, UK
⁴ Central and North West London NHS Foundation Trust, London, UK
⁵ School of Healthcare, University of Leeds, Leeds, UK
⁶ Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK
⁷ Oxleas NHS Foundation Trust, Kent, UK
⁸ Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK
⁹ West London NHS Trust, London, UK
^* Corresponding author Email: m.crawford@imperial.ac.uk

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