Carer administration of as-needed subcutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT

Poolman, Marlise; Roberts, Jessica; Wright, Stella; Hendry, Annie; Goulden, Nia; Holmes, Emily AF; Byrne, Anthony; Perkins, Paul; Hoare, Zoe; Nelson, Annmarie; Hiscock, Julia; Hughes, Dyfrig; O’Connor, Julie; Foster, Betty; Reymond, Liz; Healy, Sue; Lewis, Penney; Wee, Bee; Johnstone, Rosalynde; Roberts, Rossela; Parkinson, Anne; Roberts, Sian; Wilkinson, Clare

doi:10.3310/hta24250

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Carer administration of subcutaneous medication was acceptable and feasible, but low recruitment overall and low retention in the usual care group indicate the success of a future trial may be uncertain.

Marlise Poolman , Jessica Roberts , Stella Wright , Annie Hendry , Nia Goulden , Emily AF Holmes , Anthony Byrne , Paul Perkins , Zoe Hoare , Annmarie Nelson , Julia Hiscock , Dyfrig Hughes , Julie O’Connor, Betty Foster, Liz Reymond , Sue Healy , Penney Lewis , Bee Wee , Rosalynde Johnstone , Rossela Roberts , Anne Parkinson , Sian Roberts & Clare Wilkinson .

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Marlise Poolman ^1,^*, Jessica Roberts ¹, Stella Wright ¹, Annie Hendry ¹, Nia Goulden ², Emily AF Holmes ¹, Anthony Byrne ³, Paul Perkins ^4,⁵, Zoe Hoare ², Annmarie Nelson ³, Julia Hiscock ¹, Dyfrig Hughes ¹, Julie O’Connor ⁵, Betty Foster ⁶, Liz Reymond ⁷, Sue Healy ⁸, Penney Lewis ⁹, Bee Wee ¹⁰, Rosalynde Johnstone ¹¹, Rossela Roberts ¹², Anne Parkinson ⁵, Sian Roberts ¹¹, Clare Wilkinson ¹

¹ School of Health Sciences, Bangor University, Bangor, UK
² North Wales Organisation for Randomised Trials in Health, Bangor University, Bangor, UK
³ Marie Curie Research Centre, School of Medicine, Cardiff University, Cardiff, UK
⁴ Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK
⁵ Sue Ryder Leckhampton Court Hospice, Cheltenham, UK
⁶ Public Contributor, North Wales Cancer Patient Forum, North Wales Cancer Treatment Centre, Bodelwyddan, UK
⁷ Brisbane South Palliative Care Collaborative, School of Medicine, Griffith University, Southport, QLD, Australia
⁸ Metro South Palliative Care Service, Brisbane, QLD, Australia
⁹ Centre for Medical Law and Ethics, King’s College London, London, UK
¹⁰ Harris Manchester College, University of Oxford, Oxford, UK
¹¹ Betsi Cadwaladr University Health Board, Bangor, UK
¹² School of Psychology, Bangor University, Bangor, UK
^* Corresponding author Email: m.poolman@bangor.ac.uk

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