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Point-of-care testing resulted in a 20% absolute reduction in patient-reported antibiotic consumption over 4 weeks, without impairing chronic obstructive pulmonary disease health status.

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Nick A Francis 1,*, David Gillespie 2, Patrick White 3, Janine Bates 2, Rachel Lowe 2, Bernadette Sewell 4, Rhiannon Phillips 1, Helen Stanton 2, Nigel Kirby 2, Mandy Wootton 5, Emma Thomas-Jones 2, Kerenza Hood 2, Carl Llor 6, Jochen Cals 7, Hasse Melbye 8, Gurudutt Naik 9, Micaela Gal 10, Deborah Fitzsimmons 4, Mohammed Fasihul Alam 11, Evgenia Riga 12, Ann Cochrane 3, Christopher C Butler 13

1 Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK
2 South East Wales Trials Unit, Centre for Trials Research, Cardiff University, Cardiff, UK
3 Department of Primary Care & Public Health Sciences, King’s College London, London, UK
4 Swansea Centre for Health Economics, College of Human and Health Sciences, Swansea University, Swansea, UK
5 Specialist Antimicrobial Chemotherapy Unit, University Hospital of Wales, Cardiff, UK
6 University Institute in Primary Care Research Jordi Gol, Via Roma Health Centre, Barcelona, Spain
7 Department of Family Medicine, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands
8 General Practice Research Unit, Department of Community Medicine, Faculty of Health Sciences, University of Tromsø – The Arctic University of Norway, Tromsø, Norway
9 Department of Wound Healing, University Hospital Wales, Cardiff, UK
10 Wales Primary and Emergency Care Research Centre, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK
11 Department of Public Health, College of Health Sciences, Qatar University, Doha, Qatar
12 Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
13 Primary Care and Vaccines Collaborative Clinical Trials Unit, University of Oxford, John Radcliffe Hospital, Oxford, UK
* Corresponding author Email:

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