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Adding adalimumab to methotrexate reduced the average risk over time of treatment failure in refractory uveitis associated with juvenile idiopathic arthritis by 75%.

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Athimalaipet V Ramanan 1,2,*, Andrew D Dick 3,4,5, Ashley P Jones 6, Dyfrig A Hughes 7, Andrew McKay 6, Anna Rosala-Hallas 6, Paula R Williamson 6, Ben Hardwick 6, Helen Hickey 6, Naomi Rainford 6, Graeme Hickey 6, Ruwanthi Kolamunnage-Dona 6, Giovanna Culeddu 7, Catrin Plumpton 7, Eifiona Wood 7, Sandrine Compeyrot-Lacassagne 8, Patricia Woo 8, Clive Edelsten 8, Michael W Beresford 9,10

1 Department of Paediatric Rheumatology, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
2 Bristol Medical School, University of Bristol, Bristol, UK
3 Bristol Eye Hospital, Bristol, UK
4 School of Clinical Sciences, University of Bristol, Bristol, UK
5 University College London Institute of Ophthalmology and National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK
6 Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, Liverpool, UK
7 Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK
8 Great Ormond Street Hospital, London, UK
9 Department of Paediatric Rheumatology, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
10 Department of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool, UK
* Corresponding author Email: avramanan@hotmail.com

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