Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study

Brown, Louise Clare; Ahmed, Hashim U; Faria, Rita; El-Shater Bosaily, Ahmed; Gabe, Rhian; Kaplan, Richard S; Parmar, Mahesh; Collaco-Moraes, Yolanda; Ward, Katie; Hindley, Richard Graham; Freeman, Alex; Kirkham, Alexander; Oldroyd, Robert; Parker, Chris; Bott, Simon; Burns-Cox, Nick; Dudderidge, Tim; Ghei, Maneesh; Henderson, Alastair; Persad, Rajendra; Rosario, Derek J; Shergill, Iqbal; Winkler, Mathias; Soares, Marta; Spackman, Eldon; Sculpher, Mark; Emberton, Mark

doi:10.3310/hta22390

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Adding multiparametric MRI as an initial test prior to prostate biopsy can reduce the proportion of men having unnecessary biopsies and improve the detection of clinically significant prostate cancer.

Louise Clare Brown , Hashim U Ahmed , Rita Faria , Ahmed El-Shater Bosaily , Rhian Gabe , Richard S Kaplan , Mahesh Parmar , Yolanda Collaco-Moraes , Katie Ward , Richard Graham Hindley , Alex Freeman , Alexander Kirkham , Robert Oldroyd , Chris Parker, Simon Bott, Nick Burns-Cox , Tim Dudderidge , Maneesh Ghei , Alastair Henderson , Rajendra Persad , Derek J Rosario , Iqbal Shergill , Mathias Winkler , Marta Soares , Eldon Spackman , Mark Sculpher & Mark Emberton .

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Louise Clare Brown ¹, Hashim U Ahmed ^2,^3,^*, Rita Faria ⁴, Ahmed El-Shater Bosaily ^2,³, Rhian Gabe ⁵, Richard S Kaplan ¹, Mahesh Parmar ¹, Yolanda Collaco-Moraes ¹, Katie Ward ¹, Richard Graham Hindley ⁶, Alex Freeman ⁷, Alexander Kirkham ⁸, Robert Oldroyd ⁹, Chris Parker ¹⁰, Simon Bott ¹¹, Nick Burns-Cox ¹², Tim Dudderidge ¹³, Maneesh Ghei ¹⁴, Alastair Henderson ¹⁵, Rajendra Persad ¹⁶, Derek J Rosario ¹⁷, Iqbal Shergill ¹⁸, Mathias Winkler ¹⁹, Marta Soares ⁴, Eldon Spackman ⁴, Mark Sculpher ⁴, Mark Emberton ^2,³

¹ Medical Research Council Clinical Trials Unit, University College London, London, UK
² Division of Surgery and Interventional Science, Faculty of Medical Sciences, University College London, London, UK
³ Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK
⁴ Centre for Health Economics, University of York, York, UK
⁵ Hull York Medical School and Department of Health Sciences, University of York, York, UK
⁶ Department of Urology, Hampshire Hospitals NHS Foundation Trust, Basingstoke, UK
⁷ Department of Histopathology, University College London Hospitals NHS Foundation Trust, London, UK
⁸ Department of Radiology, University College London Hospitals NHS Foundation Trust, London, UK
⁹ Public and patient representative, Nottingham, UK
¹⁰ Department of Academic Urology, Royal Marsden Hospital, Sutton, UK
¹¹ Frimley Park Hospital, Frimley, UK
¹² Musgrove Park Hospital, Taunton, UK
¹³ Southampton General Hospital, Southampton, UK
¹⁴ Department of Urology, Whittington Hospital, London, UK
¹⁵ Maidstone Hospital, Maidstone, UK
¹⁶ Bristol Urological Institute, Southmead Hospital, Bristol, UK
¹⁷ Royal Hallamshire Hospital, Sheffield, UK
¹⁸ Wrexham Maelor Hospital, Wrexham, UK
¹⁹ Charing Cross Hospital, Imperial College London, London, UK
^* Corresponding author Email: hashim.ahmed@imperial.ac.uk

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