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The trial did not meet the criteria for progression, with 17% of eligible patients randomised, and a full trial is not presently possible.

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Naeem Soomro 1,*, Jan Lecouturier 2, Deborah D Stocken 2,3, Jing Shen 2, Ann Marie Hynes 3, Holly F Ainsworth 2, David Breen 4, Grenville Oades 5, David Rix 1, Michael Aitchison 6

1 The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
2 Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
3 Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK
4 University Hospital Southampton NHS Foundation Trust, Southampton, UK
5 NHS Greater Glasgow and Clyde Health Board, Glasgow, UK
6 Royal Free London NHS Foundation Trust, London, UK
* Corresponding author Email: naeem.soomro@nuth.nhs.uk

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