The clinical effectiveness and cost-effectiveness of cetuximab (review of technology appraisal no. 176) and panitumumab (partial review of technology  appraisal no. 240) for previously untreated metastatic colorectal cancer: a systematic review and economic evaluation

Huxley, Nicola; Crathorne, Louise; Varley-Campbell, Jo; Tikhonova, Irina; Snowsill, Tristan; Briscoe, Simon; Peters, Jaime; Bond, Mary; Napier, Mark; Hoyle, Martin

doi:10.3310/hta21380

An error occurred retrieving content to display, please try again.

Page not found (404)

Sorry - the page you requested could not be found.

Please choose a page from the navigation or try a website search above to find the information you need.

Toolkit

View Project

In previously untreated RAS WT metastatic colorectal cancer, adding either cetuximab or panitumumab to chemotherapy produced benefits for patients, but neither was likely to be good value for money for the NHS.

Huxley N, Crathorne L, Varley-Campbell J, Tikhonova I, Snowsill T, Briscoe S, Peters J, Bond M, Napier M & Hoyle M.

Detailed Author information
Detailed Author information

Nicola Huxley ^1,^*, Louise Crathorne ¹, Jo Varley-Campbell ¹, Irina Tikhonova ¹, Tristan Snowsill ¹, Simon Briscoe ¹, Jaime Peters ¹, Mary Bond ¹, Mark Napier ², Martin Hoyle ¹

¹ Peninsula Technology Assessment Group (PenTAG), University of Exeter Medical School, Exeter, UK
² Royal Devon and Exeter NHS Foundation Trust, Exeter, UK
^* Corresponding author Email: nicola.huxley@monash.edu

Funding: {{metadata.Funding}}

{{metadata.Journal}} Volume: {{metadata.Volume}}, Issue: {{metadata.Issue}}, Published in {{metadata.PublicationDate | date:'MMMM yyyy'}}

https://doi.org/{{metadata.DOI}}

Citation: {{author}}{{ (($index < metadata.AuthorsArray.length-1) && ($index <=6)) ? ', ' : '' }}{{(metadata.AuthorsArray.length <= 6) ? '.' : '' }} {{(metadata.AuthorsArray.length > 6) ? 'et al.' : ''}} {{metadata.Title}}. {{metadata.JournalShortName}} {{metadata.PublicationDate | date:'yyyy'}};{{metadata.Volume}}({{metadata.Issue}})

Report Content

Full Report
Abstract
Plain English Summary
Scientific Summary

The full text of this issue is available as a PDF document from the Toolkit section on this page.

Responses to this report

No responses have been published.

If you would like to submit a response to this publication, please do so using the form below:

Comments submitted to the NIHR Journals Library are electronic letters to the editor. They enable our readers to debate issues raised in research reports published in the Journals Library. We aim to post within 2 working days all responses that contribute substantially to the topic investigated, as determined by the Editors.

Your name and affiliations will be published with your comment.

Once published, you will not have the right to remove or edit your response. The Editors may add, remove, or edit comments at their absolute discretion.

Enter response message*

Name (title, first name, last name)*

Occupation / Job title*

Affiliation / Employer*

Email*

Other authors
For example, if you are responding as a team or group. Please ensure you include full names and separate these using commas

Statement of competing interests
We believe that readers should be aware of any competing interests (conflicts of interest).
The International Committee of Medical Journal Editors (ICMJE) define competing interests as including: financial relationships with industry (for example through employment, consultancies, stock, ownership, honoraria, and expert testimony), either directly or through immediate family; personal relationships; academic competition; and intellectual passion.

If yes, please provide details below

Enter response title*

Enter CAPTCHA What is thirty divided by five?*

By submitting your response, you are stating that you agree to the terms & conditions