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After conservative breast surgery for early breast cancer, targeted intra-operative radiotherapy was non-inferior in terms of local recurrence at 5 years compared with conventional post-operative radiotherapy and was possibly cost-saving.

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Jayant S Vaidya, Frederik Wenz, Max Bulsara, Jeffrey S Tobias, David J Joseph, Christobel Saunders, Chris Brew-Graves, Ingrid Potyka, Stephen Morris, Hrisheekesh J Vaidya, Norman R Williams & Michael Baum.

Jayant S Vaidya 1,2,*, Frederik Wenz 3, Max Bulsara 4, Jeffrey S Tobias 5, David J Joseph 6, Christobel Saunders 7, Chris Brew-Graves 1, Ingrid Potyka 1, Stephen Morris 8, Hrisheekesh J Vaidya 9, Norman R Williams 1, Michael Baum 1

1 Division of Surgery and Interventional Science, University College London, London, UK
2 Department of Surgery, Whittington Hospital, Royal Free Hospital and University College London Hospital, London, UK
3 Department of Radiation Oncology, University Medical Centre Mannheim, University of Heidelberg, Heidelberg, Germany
4 Department of Biostatistics, University of Notre Dame, Fremantle, WA, Australia
5 Department of Clinical Oncology, University College London Hospitals, London, UK
6 Department of Radiation Oncology, Sir Charles Gairdner Hospital, Perth, WA, Australia
7 Department of Surgery, University of Western Australia, Perth, WA, Australia
8 Health Economics Group, Department of Biomedical Engineering, University College London, London, UK
9 Keble College, Oxford University, Oxford, UK
* Corresponding author Email:

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