Pulse oximetry as a screening test for congenital heart defects in newborn infants: a test accuracy study with evaluation of acceptability and cost-effectiveness

Ewer, AK; Furmston, AT; Middleton, LJ; Deeks, JJ; Daniels, JP; Pattison, HM; Powell, R; Roberts, TE; Barton, P; Auguste, P; Bhoyar, A; Thangaratinam, S; Tonks, AM; Satodia, P; Deshpande, S; Kumararatne, B; Sivakumar, S; Mupanemunda, R; Khan, KS

doi:10.3310/hta16020

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Study finds that pulse oximetry is a safe, accurate test that is acceptable to parents and staff as a screening test for congenital heart defects (CHDs) in newborn infants. It is likely to identify cases of critical CHDs that would otherwise go undetected and is expected to be cost-effective.

AK Ewer, AT Furmston, LJ Middleton, JJ Deeks, JP Daniels, HM Pattison, R Powell, TE Roberts, P Barton, P Auguste, A Bhoyar, S Thangaratinam, AM Tonks, P Satodia, S Deshpande, B Kumararatne, S Sivakumar, R Mupanemunda & KS Khan.

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AK Ewer ^1,^2,^*, AT Furmston ³, LJ Middleton ³, JJ Deeks ⁴, JP Daniels ^1,³, HM Pattison ⁵, R Powell ⁵, TE Roberts ⁶, P Barton ⁶, P Auguste ⁶, A Bhoyar ⁷, S Thangaratinam ^1,², AM Tonks ⁸, P Satodia ⁹, S Deshpande ¹⁰, B Kumararatne ¹¹, S Sivakumar ¹², R Mupanemunda ¹³, KS Khan ¹⁴

¹ University of Birmingham, School of Clinical and Experimental Medicine, Birmingham, UK
² Birmingham Women’s Healthcare NHS Foundation Trust, Birmingham, UK
³ University of Birmingham, Birmingham Clinical Trials Unit, Birmingham, UK
⁴ University of Birmingham, Public Health, Epidemiology and Biostatistics, Birmingham, UK
⁵ Aston University, School of Life and Health Sciences, Birmingham, UK
⁶ University of Birmingham, Health Economics Unit, School of Health and Population Sciences, Birmingham, UK
⁷ Birmingham Children’s Hospital NHS Foundation Trust, Birmingham, UK
⁸ West Midlands Perinatal Institute, Birmingham, UK
⁹ University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK
¹⁰ The Shrewsbury and Telford Hospital NHS Trust, Shrewsbury, UK
¹¹ The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK
¹² Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK
¹³ Heart of England NHS Foundation Trust, Birmingham, UK
¹⁴ Barts and the London School of Medicine and Dentistry, London, UK
^* Corresponding author Email: a.k.ewer@bham.ac.uk

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