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Only 360 deg; cryotherapy and focal and circumferential laser treatment have been evaluated for the type 1 Stickler syndrome population, and then only by a single retrospective, controlled, cohort study in each case. Both of these studies report a significant difference between intervention and control groups (principally no treatment) and no major or long-term side effects or complications. However, there is a high risk of bias within these two studies, so the relative effectiveness of either intervention is uncertain
The University of Sheffield, School of Health and Related Research (ScHARR), Sheffield, UK
* Corresponding author Email: c.carroll@sheffield.ac.uk
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