Impact of video-assisted thoracoscopic lobectomy versus open lobectomy for lung cancer on recovery assessed using self-reported physical function: VIOLET RCT

Lim, Eric; Harris, Rosie A; McKeon, Holly E; Batchelor, Timothy JP; Dunning, Joel; Shackcloth, Michael; Anikin, Vladimir; Naidu, Babu; Belcher, Elizabeth; Loubani, Mahmoud; Zamvar, Vipin; Dabner, Lucy; Brush, Timothy; Stokes, Elizabeth A; Wordsworth, Sarah; Paramasivan, Sangeetha; Realpe, Alba; Elliott, Daisy; Blazeby, Jane; Rogers, Chris A

doi:10.3310/THBQ1793

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This trial showed that video assisted thoracoscopic lobectomy was associated with better physical function at five weeks and improved quality of life, while producing a cost saving.

Eric Lim , Rosie A Harris , Holly E McKeon , Timothy JP Batchelor , Joel Dunning , Michael Shackcloth , Vladimir Anikin , Babu Naidu , Elizabeth Belcher , Mahmoud Loubani , Vipin Zamvar , Lucy Dabner , Timothy Brush , Elizabeth A Stokes , Sarah Wordsworth , Sangeetha Paramasivan , Alba Realpe , Daisy Elliott , Jane Blazeby & Chris A Rogers .

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Eric Lim ^1,^*, Rosie A Harris ², Holly E McKeon ², Timothy JP Batchelor ³, Joel Dunning ⁴, Michael Shackcloth ⁵, Vladimir Anikin ¹, Babu Naidu ⁶, Elizabeth Belcher ⁷, Mahmoud Loubani ⁸, Vipin Zamvar ⁹, Lucy Dabner ², Timothy Brush ², Elizabeth A Stokes ^10,¹¹, Sarah Wordsworth ^10,¹¹, Sangeetha Paramasivan ¹², Alba Realpe ¹², Daisy Elliott ¹³, Jane Blazeby ¹³, Chris A Rogers ²

¹ Academic Division of Thoracic Surgery, The Royal Brompton and Harefield Hospitals, London, UK
² Clinical Trials and Evaluation Unit, Bristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, UK
³ Thoracic Surgery, Bristol Royal Infirmary, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK
⁴ Department of Cardiothoracic Surgery, The James Cook University Hospital, South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK
⁵ Department of Thoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK
⁶ Department of Thoracic Surgery, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK
⁷ Cardiothoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
⁸ Department of Cardiothoracic Surgery, Castle Hill Hospital, Cottingham, UK
⁹ Department of Cardiothoracic Surgery, Edinburgh Royal Infirmary, Edinburgh, UK
¹⁰ Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
¹¹ National Institute for Health and Care Research Oxford Biomedical Research Centre, Oxford, UK
¹² Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
¹³ National Institute for Health and Care Research Bristol and Weston Biomedical Research Centre, Surgical Innovation Theme, Centre for Surgical Research, Bristol Medical School, University of Bristol, Bristol, UK
^* Corresponding author Email: e.lim@rbht.nhs.uk

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