Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation: RCT and systematic review

Metwally, Mostafa; Chatters, Robin; Pye, Clare; Dimairo, Munya; White, David; Walters, Stephen; Cohen, Judith; Young, Tracey; Cheong, Ying; Laird, Susan; Mohiyiddeen, Lamiya; Chater, Tim; Pemberton, Kirsty; Turtle, Chris; Hall, Jamie; Taylor, Liz; Brian, Kate; Sizer, Anya; Hunter, Helen

doi:10.3310/JNZT9406

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This trial and the subsequent review showed that performing endometrial scratch prior to the first cycle of IVF did not increase live birth rates compared with IVF without this procedure.

Mostafa Metwally , Robin Chatters , Clare Pye , Munya Dimairo , David White , Stephen Walters , Judith Cohen , Tracey Young , Ying Cheong , Susan Laird , Lamiya Mohiyiddeen , Tim Chater , Kirsty Pemberton , Chris Turtle , Jamie Hall , Liz Taylor , Kate Brian , Anya Sizer & Helen Hunter .

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Mostafa Metwally ^1,^*, Robin Chatters ², Clare Pye ¹, Munya Dimairo ², David White ², Stephen Walters ³, Judith Cohen ⁴, Tracey Young ⁵, Ying Cheong ⁶, Susan Laird ⁷, Lamiya Mohiyiddeen ⁸, Tim Chater ², Kirsty Pemberton ², Chris Turtle ², Jamie Hall ², Liz Taylor ¹, Kate Brian ⁹, Anya Sizer ⁹, Helen Hunter ¹⁰

¹ Assisted Conception Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
² Sheffield Clinical Trials Research Unit (CTRU), School of Health and Related Research (ScHARR), The University of Sheffield, Sheffield, UK
³ Design, Trials and Statistics, School of Health and Related Research (ScHARR), Sheffield, UK
⁴ Hull Health Trials Unit, University of Hull, Hull, UK
⁵ Health Economic and Decision Science, School of Health and Related Research (ScHARR), Sheffield, UK
⁶ Faculty of Medicine, University of Southampton, Southampton, UK
⁷ Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield, UK
⁸ Saint Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester, UK
⁹ Fertility Network UK, Greenwich, UK
¹⁰ Department of Reproductive Medicine, Old St Mary’s Hospital, Manchester, UK
^* Corresponding author Email: Mmetwally@sheffield.ac.uk

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