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This study was terminated at the end of the pilot phase due to poor recruitment resulting from lower-than-expected disease prevalence and difficulties identifying the condition at a sufficiently early stage.

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Sion Glyn-Jones 1,*, Muhammad K Javaid 1, David Beard 1,2, Julia Newton 1, Robert Kerslake 3, Callum McBryde 4, Tim Board 5, Susan J Dutton 1,6, Melina Dritsaki 1,6, Vikas Khanduja 7, Magbor Akanni 8, Shaun Sexton 9, John Skinner 10, Nicholas Peckham 1,6, Ruth Knight 1,6, Ines Rombach 1,6, Loretta Davies 1,2, Vicki Barber 1,6

1 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
2 Surgical Intervention Trials Unit, University of Oxford, Oxford, UK
3 Trauma and Orthopaedic Department, Nottingham University Hospitals NHS Trust, Nottingham, UK
4 Orthopaedic Department, The Royal Orthopaedic Hospital NHS Foundation Trust, Birmingham, UK
5 Orthopaedic Hip Unit, Wrightington Hospital, Wigan and Leigh NHS Foundation Trust, Wigan, UK
6 Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK
7 Trauma and Orthopaedics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
8 Trauma and Orthopaedics, Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes, UK
9 Trauma & Orthopaedics, Royal Cornwall Hospitals NHS Trust, Truro, UK
10 Orthopaedic Department, Royal National Orthopaedic Hospital NHS Trust, Stanmore, UK
* Corresponding author Email: sion.glyn-jones@ndorms.ox.ac.uk

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