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This study showed the links identified may be the 'best-bets' for interventions that are effective in changing mechanisms of action and the non-links are unlikely to be effective.

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Susan Michie 1,*, Marie Johnston 2, Alexander J Rothman 3, Marijn de Bruin 2,4, Michael P Kelly 5, Rachel N Carey 1, Lauren EC Bohlen 1,6, Hilary NK Groarke 7, Niall C Anderson 1,8, Silje Zink 1,9

1 Centre for Behaviour Change, University College London, London, UK
2 Institute of Applied Health Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, UK
3 Department of Psychology, University of Minnesota, Minneapolis, MN, USA
4 Radboud University Medical Center, Radboud Institute for Health Sciences, IQ Healthcare, Nijmegen, the Netherlands
5 Primary Care Unit, Cambridge Institute of Public Health, University of Cambridge, Cambridge, UK
6 Department of Kinesiology, College of Health Sciences, University of Rhode Island, Kingston, RI, USA
7 Department of Psychology, National University of Ireland Galway, Galway, Ireland
8 National Institute for Health Research (NIHR) Health Protection Research Unit in Behavioural Science and Evaluation, University of Bristol, Bristol, UK
9 National Advisory Unit on Rehabilitation in Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
* Corresponding author Email:

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