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This study provided enhancements to the risk models underpinning national clinical audits, which may assist in providing objective estimates of potential outcomes for patients and their families.

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Paloma Ferrando-Vivas 1, Manu Shankar-Hari 2,3, Karen Thomas 1, James C Doidge 1, Fergus J Caskey 4,5, Lui Forni 6, Steve Harris 7,8, Marlies Ostermann 9, Ivan Gornik 10, Naomi Holman 11, Nazir Lone 12, Bob Young 13, David Jenkins 14, Stephen Webb 15, Jerry P Nolan 16,17, Jasmeet Soar 18, Kathryn M Rowan 1, David A Harrison 1,*

1 Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK
2 Intensive Care Unit, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
3 School of Immunology & Microbial Sciences, Kings College London, London, UK
4 Population Health Sciences, University of Bristol, Bristol, UK
5 Department of Renal Medicine, North Bristol NHS Trust, Bristol, UK
6 Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University of Surrey, Guildford, UK
7 Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, UK
8 Bloomsbury Institute for Intensive Care Medicine, Division of Medicine, University College London, London, UK
9 Department of Critical Care, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
10 Intensive Care Unit, University Hospital Centre Zagreb, Zagreb, Croatia
11 Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, UK
12 Usher Institute, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
13 Diabetes UK, London, UK
14 Department of Cardiothoracic Surgery, Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK
15 Department of Anaesthesia and Intensive Care, Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK
16 Warwick Medical School, University of Warwick, Coventry, UK
17 Department of Anaesthesia and Intensive Care Medicine, Royal United Hospital Bath NHS Trust, Bath, UK
18 Critical Care Unit, Southmead Hospital, North Bristol NHS Trust, Bristol, UK
* Corresponding author Email: david.harrison@icnarc.org

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