Co-trimoxazole to reduce mortality, transplant, or unplanned hospitalisation in people with moderate to very severe idiopathic pulmonary fibrosis: the EME-TIPAC RCT

Wilson, Andrew M; Clark, Allan B; Cahn, Anthony; Chilvers, Edwin R; Fraser, William; Hammond, Matthew; Livermore, David M; Maher, Toby M; Parfrey, Helen; Swart, Ann Marie; Stirling, Susan; Thickett, David; Whyte, Moira

doi:10.3310/eme08090

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This trial showed that co-trimoxazole did not reduce death or hospitalisations in people with moderate to very severe idiopathic pulmonary fibrosis.

Andrew M Wilson , Allan B Clark , Anthony Cahn , Edwin R Chilvers , William Fraser , Matthew Hammond , David M Livermore , Toby M Maher , Helen Parfrey , Ann Marie Swart , Susan Stirling , David Thickett & Moira Whyte .

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Andrew M Wilson ^1,^*, Allan B Clark ¹, Anthony Cahn ², Edwin R Chilvers ³, William Fraser ¹, Matthew Hammond ⁴, David M Livermore ¹, Toby M Maher ⁵, Helen Parfrey ⁶, Ann Marie Swart ⁴, Susan Stirling ⁴, David Thickett ⁷, Moira Whyte ⁸

¹ Norwich Medical School, University of East Anglia, Norwich, UK
² Department of Respiratory Medicine, Bedford Hospitals NHS Trust, Bedford, UK
³ ICTEM building, Hammersmith Campus, Imperial College London, London, UK
⁴ Norwich Clinical Trials Unit, University of East Anglia, Norwich, UK
⁵ Department of Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, Royal Brompton Hospital, London, UK
⁶ Department of Respiratory Medicine, Royal Papworth Hospital NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, UK
⁷ Birmingham Acute Care Research Group, University of Birmingham, Birmingham, UK
⁸ Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK
^* Corresponding author Email: a.m.wilson@uea.ac.uk

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