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A methylation assay was developed that showed promise, but it failed to demonstrate added diagnostic value over colonoscopy alone in the context of the ulcerative colitis surveillance programme.

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Ashish AwasthiORCID logo, Jamie BarbourORCID logo, Andrew BeggsORCID logo, Pradeep BhandariORCID logo, Daniel BlakewayORCID logo, Matthew BrookesORCID logo, James BrownORCID logo, Matthew BrownORCID logo, Germaine CaldwellORCID logo, Samuel ClokieORCID logo, Ben ColleypriestORCID logo, Abby ConlinORCID logo, Shanika de SilvaORCID logo, John de CaesteckerORCID logo, Jonathan DeeksORCID logo, Anjan DharORCID logo, Mark DilworthORCID logo, Edward FogdenORCID logo, Stephen FoleyORCID logo, Deb GhoshORCID logo, Leonie GrellierORCID logo, Ailsa HartORCID logo, Syed Samiul HoqueORCID logo, Marietta IacucciORCID logo, Tariq IqbalORCID logo, Jonathan JamesORCID logo, Mark JarvisORCID logo, Anthoor JayaprakashORCID logo, Satish KeshavORCID logo, Laura MagillORCID logo, Glenn MatthewsORCID logo, Joel MawdsleyORCID logo, Simon McLaughlinORCID logo, Samir MehtaORCID logo, Kevin MonahanORCID logo, Dion MortonORCID logo, Senthil MurugesanORCID logo, Miles ParkesORCID logo, Valerie PestingerORCID logo, Chris ProbertORCID logo, Arvind RamadasORCID logo, Alessandro RettinoORCID logo, Shaji SebastianORCID logo, Naveen SharmaORCID logo, Michael GriffithsORCID logo, Joanne StocktonORCID logo, Venkat SubramanianORCID logo, Nigel SuggettORCID logo, Philippe TaniereORCID logo, Julian TeareORCID logo, Ajay M VermaORCID logo & Yvonne WallisORCID logo.

Ashish Awasthi 1, Jamie Barbour 2, Andrew Beggs 3, Pradeep Bhandari 4, Daniel Blakeway 3, Matthew Brookes 5, James Brown 6, Matthew Brown 7, Germaine Caldwell 3, Samuel Clokie 8, Ben Colleypriest 9, Abby Conlin 10, Shanika de Silva 11, John de Caestecker 12, Jonathan Deeks 6,13, Anjan Dhar 14, Mark Dilworth 3, Edward Fogden 15, Stephen Foley 16, Deb Ghosh 17, Leonie Grellier 18, Ailsa Hart 19, Syed Samiul Hoque 20, Marietta Iacucci 21, Tariq Iqbal 3,21, Jonathan James 3, Mark Jarvis 22, Anthoor Jayaprakash 23, Satish Keshav 24, Laura Magill 6, Glenn Matthews 3, Joel Mawdsley 25, Simon McLaughlin 26, Samir Mehta 6, Kevin Monahan 25, Dion Morton 3,21,*, Senthil Murugesan 27, Miles Parkes 28, Valerie Pestinger 3, Chris Probert 29, Arvind Ramadas 30, Alessandro Rettino 8, Shaji Sebastian 31, Naveen Sharma 21,32, Michael Griffiths 8, Joanne Stockton 3, Venkat Subramanian 33, Nigel Suggett 21, Philippe Taniere 21, Julian Teare 34, Ajay M Verma 35, Yvonne Wallis 8

1 Department of Gastroenterology, Manor Hospital, Walsall, UK
2 Department of Inflammatory Bowel Disease, Queen Elizabeth Hospital, Gateshead, UK
3 Institute of Cancer and Genomic Science, University of Birmingham, Birmingham, UK
4 Department of Gastroenterology, Queen Alexandra Hospital Portsmouth, Portsmouth, UK
5 Department of Gastroenterology, New Cross Hospital, Wolverhampton, UK
6 Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK
7 Department of Gastroenterology, Basingstoke and North Hampshire Hospital, Basingstoke, UK
8 West Midlands Regional Genetics Laboratory, Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK
9 Department of Gastroenterology, Royal United Hospital Bath, Bath, UK
10 Department of Gastroenterology, Salford Royal Hospital, Manchester, UK
11 Department of Gastroenterology, Russells Hall Hospital, Dudley, UK
12 Department of Gastroenterology, University Hospitals Leicester, Leicester, UK
13 National Institute for Health Research (NIHR) Birmingham Inflammation Biomedical Research Centre, Birmingham, UK
14 Department of Gastroenterology, Directorate of Medicine and Acute Care, County Durham and Darlington NHS Foundation Trust, Durham, UK
15 Department of Gastroenterology, City Hospital, Birmingham, UK
16 Department of Gastroenterology, King’s Mill Hospital, Sutton-in-Ashfield, UK
17 Department of Gastroenterology, Princess Alexandra Hospital, Harlow, UK
18 Department of Gastroenterology, Newport, Isle of Wight, UK
19 Department of Gastroenterology and Inflammatory Bowel Unit, St Mark’s Hospital and Academic Institute, Middlesex, UK
20 Department of Gastroenterology, Whipps Cross Hospital, London, UK
21 University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
22 Department of Gastroenterology, Basildon and Thurrock University Hospital, Essex, UK
23 Department of Gastroenterology, North Tyneside General Hospital, North Shields, UK
24 Gastroenterology Unit, John Radcliffe Hospital, Oxford, UK
25 Department of Gastroenterology, West Middlesex University Hospital, Middlesex, UK
26 Department of Gastroenterology, Royal Bournemouth Hospital, Bournemouth, UK
27 Department of Gastroenterology, Blackpool Victoria Hospital, Blackpool, UK
28 Department of Gastroenterology, Addenbrookes Hospital, Cambridge, UK
29 Department of Gastroenterology, Institute for Translational Medicine, Royal Liverpool and Broadgreen University Hospitals, Liverpool, UK
30 Department of Gastroenterology, James Cook University Hospital, Middlesbrough, UK
31 Department of Gastroenterology, Hull Royal Infirmary, Hull, UK
32 Department of Gastroenterology, Heartlands Hospital, Birmingham, UK
33 Department of Gastroenterology, St James’s University Hospital, Leeds, UK
34 Department of Gastroenterology, St Mary’s Hospital, London, UK
35 Department of Gastroenterology, Kettering General Hospital, Kettering, UK
* Corresponding author Email:

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