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At one year, intravitreal aflibercept improved visual acuity more than panretinal photocoagulation, costing £5475 more in total resource use.

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Sobha Sivaprasad 1,2,*, Philip Hykin 1, A Toby Prevost 3, Joana Vasconcelos 3, Amy Riddell 4, Jayashree Ramu 1, Caroline Murphy 4, Joanna Kelly 4, Rhiannon Tudor Edwards 5, Seow Tien Yeo 5, James Bainbridge 2, David Hopkins 6, Beverley White-Alao 4

1 National Institute for Health Research Clinical Research Facility, Moorfields Biomedical Research Centre, London, UK
2 University College London Institute of Ophthalmology, London, UK
3 Imperial Clinical Trials Unit, School of Public Health, Imperial College London, London, UK
4 King’s Clinical Trials Unit King’s College London, London, UK
5 Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK
6 Department of Diabetes and Endocrinology, King’s College Hospital NHS Foundation Trust, London, UK
* Corresponding author Email:

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