Journals Library

About the EME journal


Professor John Powell

View Editors

Efficacy and Mechanism Evaluation (EME) was launched in 2014 and is indexed by NHS Evidence, Europe PMC and NCBI Bookshelf. 


Evaluations of new treatments, including those intended to prevent disease, covering:

  • therapeutics (small molecule and biologic)
  • psychological interventions
  • public health
  • diagnostics
  • medical devices

Publication criteria

Reports are published in the journal if

  1. they have resulted from work for the Efficacy and Mechanism Evaluation (EME) Programme, and
  2. they are of a sufficiently high scientific quality as assessed by the external reviewers and journal editors.

The journal will only publish findings from NIHR-funded research, therefore speculative submissions are not considered and there are no article processing charges (APCs) or article submission charges for authors.

Publication process

Final reports are delivered to the editorial office at the NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) at the University of Southampton. We manage the editorial review process between the editors, reviewers and authors, ahead of sending the report to the production house. We also co-ordinate the editorial boards, and manage the relationship with the production house. 

In preparing and submitting their EME report, researchers are expected to follow the Information for authors guidance. We take an active role in the prevention of plagiarism, falsification of data, fabrication of results and other areas of ethical misconduct. Please see the Information for authors for more information about our plagiarism policy.

Our community of reviewers plays a vital part in maintaining and improving the quality of the journal. Reviewers are usually sourced from our database of experts, from author suggestions, or from peer-to-peer recommendations. Typically, for each report, four reviewers are chosen for suitability by the editors, and will cover a variety of relevant areas in their reviews. EME has a system of single blind review, where authors do not know who has reviewed or edited their final reports. Please see our be a reviewer page for more information.

Our production house, Prepress Projects, is based in Perth, Scotland. We have a dedicated project management team at Prepress who are responsible for managing the production stage following editorial review. This involves copy-editing, typesetting and producing the electronic files of reports. When reports reach Prepress, they are copy-edited and proofread by professional writers and proof-readers who liaise directly with the report authors and editors.

All reports published in EME are open access. For further information please see the Journals Library open access statement.

The NIHR Journals Library is committed to maintaining the content it publishes and to alerting readers to changes if and when they occur.


The EME Programme funds research to evaluate new treatments, including ones intended to prevent disease, covering: therapeutics (small molecule and biologic); psychological interventions; public health; diagnostics and medical devices. View EME research projects.  

The Programme sits between and works closely with the Medical Research Council's (MRC) Experimental Medicine schemes and the NIHR Health Technology Assessment Programme.

For further information on the EME Programme and its remit, please visit the programme pages on the NIHR Evaluation, Trials and Studies (NETS) website.  Research projects currently in progress can be viewed here.