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This trial showed that FeNO-guided treatment did not reduce asthma exacerbation treated with oral corticosteroids in the year post randomisation.

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Steve Turner 1, Seonaidh Cotton 2, Jessica Wood 2, Victoria Bell 2, Edwin-Amalraj Raja 3, Neil W Scott 3, Heather Morgan 4, Louisa Lawrie 2, David Emele 2, Charlotte Kennedy 5, Graham Scotland 5, Shona Fielding 6, Graeme MacLennan 2, John Norrie 7, Mark Forrest 2, Erol Gaillard 8, Johan de Jongeste 9, Marielle Pijnenburg 9, Mike Thomas 10, David Price 11,12

1 Royal Aberdeen Children’s Hospital, University of Aberdeen, Aberdeen, UK
2 Health Services Research Unit, University of Aberdeen, Aberdeen, UK
3 Medical Statistics Team, University of Aberdeen, Aberdeen, UK
4 Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK
5 Health Economics Research Unit, University of Aberdeen, Aberdeen, UK
6 Medical Statistics Team, University of Aberdeen, Aberdeen, UK
7 Edinburgh Clinical Trials Unit, University of Edinburgh, Edinburgh, UK
8 Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK
9 Erasmus University Medical Centre, Rotterdam, the Netherlands
10 Primary Care and Population Sciences, University of Southampton, Southampton, UK
11 Observational and Pragmatic Research Institute, , Singapore
12 Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK
* Corresponding author Email: s.w.turner@abdn.ac.uk

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