Preoperative intravenous iron for anaemia in elective major open abdominal surgery: the PREVENTT RCT

Richards, Toby; Baikady, Ravishankar Rao; Clevenger, Ben; Butcher, Anna; Abeysiri, Sandy; Chau, Marisa; Swinson, Rebecca; Collier, Tim; Dodd, Matthew; Dyck, Laura Van; Macdougall, Iain; Murphy, Gavin; Browne, John; Bradbury, Andrew; Klein, Andrew

doi:10.3310/hta25110

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Preoperative intravenous iron was not superior to placebo in reducing mortality or need for blood transfusion when administered to patients with anaemia 10 42 days before elective major abdominal surgery.

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Toby Richards ^1,^2,^3,^*, Ravishankar Rao Baikady ⁴, Ben Clevenger ^3,¹¹, Anna Butcher ³, Sandy Abeysiri ^2,³, Marisa Chau ^2,³, Rebecca Swinson ⁵, Tim Collier ⁵, Matthew Dodd ⁵, Laura Van Dyck ⁵, Iain Macdougall ⁶, Gavin Murphy ⁷, John Browne ⁸, Andrew Bradbury ⁹, Andrew Klein ¹⁰

¹ Division of Surgery, University of Western Australia, Perth, WA, Australia
² Institute of Clinical Trial and Methodology, University College London, London, UK
³ Division of Surgery, University College London, London, UK
⁴ The Royal Marsden NHS Foundation Trust, London, UK
⁵ Clinical Trials Unit, London School of Hygiene & Tropical Medicine, London, UK
⁶ Department of Renal Medicine, King’s College Hospital, London, UK
⁷ NIHR Leicester Biomedical Research Centre, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
⁸ School of Public Health, University College Cork, Cork, Ireland
⁹ University Department of Vascular Surgery (University of Birmingham), Solihull Hospital, Solihull, UK
¹⁰ Department of Anaesthesia and Intensive Care, Royal Papworth Hospital, Cambridge, UK
¹¹ Department of Anaesthesia, Royal National Orthopaedic Hospital, Stanmore, UK
^* Corresponding author Email: toby.richards@uwa.edu.au

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