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This study concluded that full trials in separate settings are feasible, but it is inappropriate to combine neonatal with paediatric intensive care due to differences in treatment protocols and outcome measures.
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Lyvonne N Tume
[Image - ORCID logo], Kerry Woolfall
[Image - ORCID logo], Barbara Arch
[Image - ORCID logo], Louise Roper
[Image - ORCID logo], Elizabeth Deja
[Image - ORCID logo], Ashley P Jones
[Image - ORCID logo], Lynne Latten
[Image - ORCID logo], Nazima Pathan
[Image - ORCID logo], Helen Eccleson
[Image - ORCID logo], Helen Hickey
[Image - ORCID logo], Roger Parslow
[Image - ORCID logo], Jennifer Preston
[Image - ORCID logo], Anne Beissel
[Image - ORCID logo], Izabela Andrzejewska
[Image - ORCID logo], Chris Gale
[Image - ORCID logo], Frederic V Valla
[Image - ORCID logo] & Jon Dorling
[Image - ORCID logo].
Lyvonne N Tume 1,*, Kerry Woolfall 2, Barbara Arch 3, Louise Roper 2, Elizabeth Deja 2, Ashley P Jones 3, Lynne Latten 4, Nazima Pathan 5, Helen Eccleson 3, Helen Hickey 3, Roger Parslow 6, Jennifer Preston 7, Anne Beissel 8, Izabela Andrzejewska 9, Chris Gale 10, Frederic V Valla 11, Jon Dorling 12
1 School of Health and Society, University of Salford, Salford, UK
2 Department of Health Services Research, University of Liverpool, Liverpool, UK
3 Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK
4 Nutrition and Dietetics, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
5 Department of Paediatrics, University of Cambridge, Cambridge, UK
6 School of Medicine, University of Leeds, Leeds, UK
7 Department of Women’s and Children’s Health, Institute of Translational Medicine (Child Health), Alder Hey Children’s NHS Foundation Trust, University of Liverpool, Liverpool, UK
8 Neonatal Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon-Bron, France
9 Neonatal Unit, Chelsea and Westminster Hospital, London, UK
10 Neonatal Medicine, School of Public Health, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, London, UK
11 Paediatric Intensive Care Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon-Bron, France
12 Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada
* Corresponding author Email: l.n.tume@salford.ac.uk
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