Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

Mallucci, Conor L; Jenkinson, Michael D; Conroy, Elizabeth J; Hartley, John C; Brown, Michaela; Moitt, Tracy; Dalton, Joanne; Kearns, Tom; Griffiths, Michael J; Culeddu, Giovanna; Solomon, Tom; Hughes, Dyfrig; Gamble, Carrol; ,

doi:10.3310/hta24170

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The antibiotic-impregnated ventriculoperitoneal shunt reduced infection whereas the silver did not; the antibiotic shunt is likely to be cost-saving.

Conor L Mallucci
[Image - ORCID logo], Michael D Jenkinson
[Image - ORCID logo], Elizabeth J Conroy
[Image - ORCID logo], John C Hartley
[Image - ORCID logo], Michaela Brown
[Image - ORCID logo], Tracy Moitt
[Image - ORCID logo], Joanne Dalton
[Image - ORCID logo], Tom Kearns
[Image - ORCID logo], Michael J Griffiths
[Image - ORCID logo], Giovanna Culeddu
[Image - ORCID logo], Tom Solomon
[Image - ORCID logo], Dyfrig Hughes
[Image - ORCID logo], Carrol Gamble
[Image - ORCID logo] & .

Detailed Author information
Detailed Author information

Conor L Mallucci ^1,^*, Michael D Jenkinson ^2,³, Elizabeth J Conroy ⁴, John C Hartley ⁵, Michaela Brown ⁴, Tracy Moitt ⁴, Joanne Dalton ⁴, Tom Kearns ⁴, Michael J Griffiths ^6,⁷, Giovanna Culeddu ⁸, Tom Solomon ^6,⁹, Dyfrig Hughes ⁸, Carrol Gamble ⁴, ^†

¹ Department of Paediatric Neurosurgery, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
² Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, UK
³ Institute of Translational Medicine, University of Liverpool, Liverpool, UK
⁴ Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK
⁵ Department of Microbiology, Great Ormond Street Hospital for Children, London, UK
⁶ Institute of Infection and Global Health, University of Liverpool, Liverpool, UK
⁷ Department of Paediatric Neurology, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
⁸ Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK
⁹ Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK
^* Corresponding author Email: cmallucci@me.com

Funding: {{metadata.Funding}}

{{metadata.Journal}} Volume: {{metadata.Volume}}, Issue: {{metadata.Issue}}, Published in {{metadata.PublicationDate | date:'MMMM yyyy'}}

https://doi.org/{{metadata.DOI}}

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