Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: a RCT

Devereux, Graham; Cotton, Seonaidh; Fielding, Shona; McMeekin, Nicola; Barnes, Peter J; Briggs, Andy; Burns, Graham; Chaudhuri, Rekha; Chrystyn, Henry; Davies, Lisa; Soyza, Anthony De; Gompertz, Simon; Haughney, John; Innes, Karen; Kaniewska, Joanna; Lee, Amanda; Morice, Alyn; Norrie, John; Sullivan, Anita; Wilson, Andrew; Price, David

doi:10.3310/hta23370

Graphic version of this page | Change how these pages look

Journals Library

NHS NIHR - National Institute for Health Research

Journals

Twitter
Facebook
LinkedIn
Email

An error occurred retrieving publication content to display, please try again.

Home >> Journals >> Health Technology Assessment >> Page Not Found

Page not found (404)

Sorry - the page you requested could not be found.

Please choose a page from the navigation or try a website search above to find the information you need.

Home >> Journals >> Health Technology Assessment >> Volume {{metadata.Volume}} >> Issue {{metadata.Issue}}
Extended Research Article
i

Toolkit

View Award

Adding low-dose oral theophylline to inhaled corticosteroids did not reduce exacerbations over 1 year.

Detailed Author information
Detailed Author information

Graham Devereux ^1,^*, Seonaidh Cotton ², Shona Fielding ³, Nicola McMeekin ⁴, Peter J Barnes ⁵, Andy Briggs ⁴, Graham Burns ⁶, Rekha Chaudhuri ⁷, Henry Chrystyn ⁸, Lisa Davies ⁹, Anthony De Soyza ¹⁰, Simon Gompertz ¹¹, John Haughney ⁷, Karen Innes ², Joanna Kaniewska ², Amanda Lee ³, Alyn Morice ¹², John Norrie ¹³, Anita Sullivan ¹¹, Andrew Wilson ¹⁴, David Price ^1,¹⁵

¹ Respiratory Medicine, Aberdeen Royal Infirmary, University of Aberdeen, Aberdeen, UK
² Centre for Healthcare Randomised Trials (CHaRT), University of Aberdeen, Aberdeen, UK
³ Medical Statistics Team, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, UK
⁴ Institute of Health & Wellbeing, University of Glasgow, Glasgow, UK
⁵ National Heart and Lung Institute, Imperial College London, London, UK
⁶ Department of Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, UK
⁷ Gartnavel General Hospital, University of Glasgow, Glasgow, UK
⁸ Inhalation Consultancy Ltd, Leeds, UK
⁹ Aintree Chest Centre, University Hospital Aintree, Liverpool, UK
¹⁰ Medical School, Newcastle University, Newcastle upon Tyne, UK
¹¹ Queen Elizabeth Hospital Birmingham, Birmingham, UK
¹² Cardiovascular and Respiratory Studies, Castle Hill Hospital, Cottingham, UK
¹³ Edinburgh Clinical Trials Unit, University of Edinburgh, Edinburgh, UK
¹⁴ Department of Medicine, Norwich Medical School, University of East Anglia, Norwich, UK
¹⁵ Academic Primary Care, University of Aberdeen, Aberdeen, UK
^* Corresponding author Email: g.devereux@abdn.ac.uk

Funding: {{metadata.Funding}}

{{metadata.Journal}} Volume: {{metadata.Volume}}, Issue: {{metadata.Issue}}, Published in {{metadata.PublicationDate | date:'MMMM yyyy'}}

https://doi.org/{{metadata.DOI}}

Citation:{{author}}{{ (($index < metadata.AuthorsArray.length-1) && ($index <=6)) ? ', ' : '' }}{{(metadata.AuthorsArray.length <= 6) ? '.' : '' }} {{(metadata.AuthorsArray.length > 6) ? 'et al. ' : ''}}. {{metadata.JournalShortName}} {{metadata.PublicationDate | date:'yyyy'}};{{metadata.Volume}}({{metadata.Issue}})

[Image - Crossmark status check]

Report Content

Full Report
Abstract
Plain English Summary
Plain Language Summary
Scientific Summary

The full text of this issue is available as a PDF document from the Toolkit section on this page.

Responses to this report

No responses have been published.

If you would like to submit a response to this publication, please do so using the form below:

Comments submitted to the NIHR Journals Library are electronic letters to the editor. They enable our readers to debate issues raised in research reports published in the Journals Library. We aim to post within 14 working days all responses that contribute substantially to the topic investigated, as determined by the Editors. Non-relevant comments will be deleted.

Your name and affiliations will be published with your comment.

Once published, you will not have the right to remove or edit your response. The Editors may add, remove, or edit comments at their absolute discretion.

Enter response message*
Name (title, first name, last name)*
Occupation / Job title*
Affiliation / Employer*
Email*
Other authors
For example, if you are responding as a team or group. Please ensure you include full names and separate these using commas
Statement of competing interestsWe believe that readers should be aware of any competing interests (conflicts of interest).The International Committee of Medical Journal Editors (ICMJE) define competing interests as including: financial relationships with industry (for example through employment, consultancies, stock, ownership, honoraria, and expert testimony), either directly or through immediate family; personal relationships; academic competition; and intellectual passion.
If yes, please provide details below
Enter response title*
Enter CAPTCHA What is ten minus two?*

By submitting your response, you are stating that you agree to the terms & conditions

An error has occurred in processing the XML document