Ten-year follow-up of a randomised trial of drainage, irrigation and fibrinolytic therapy (DRIFT) in infants with post-haemorrhagic ventricular dilatation

Luyt, Karen; Jary, Sally; Lea, Charlotte; Young, Grace J; Odd, David; Miller, Helen; Kmita, Grazyna; Williams, Cathy; Blair, Peter S; Fernández, Aída Moure; Hollingworth, William; Morgan, Michelle; Smith-Collins, Adam; Thai, N Jade; Walker-Cox, Steven; Aquilina, Kristian; Pople, Ian; Whitelaw, Andrew

doi:10.3310/hta23040

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This 10-year follow-up showed that DRIFT improves cognitive function (when taking into account birth weight, grade of haemorrhage and gender), and that the incremental cost-effectiveness ratio was about £16,000.

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Karen Luyt ^1,^*, Sally Jary ¹, Charlotte Lea ¹, Grace J Young ², David Odd ^1,³, Helen Miller ¹, Grazyna Kmita ⁴, Cathy Williams ⁵, Peter S Blair ², Aída Moure Fernández ², William Hollingworth ², Michelle Morgan ⁶, Adam Smith-Collins ¹, N Jade Thai ⁷, Steven Walker-Cox ¹, Kristian Aquilina ⁸, Ian Pople ⁹, Andrew Whitelaw ¹

¹ Neonatal Neurology, University of Bristol, Bristol, UK
² Bristol Randomised Trials Collaboration, University of Bristol, Bristol, UK
³ Neonatal Medicine, North Bristol NHS Trust, Bristol, UK
⁴ Faculty of Psychology, University of Warsaw, Warsaw, Poland
⁵ Paediatric Ophthalmology, University of Bristol, Bristol, UK
⁶ Department of Psychology, Community Children’s Health Partnership, Bristol, UK
⁷ Clinical Research and Imaging Centre, Bristol, UK
⁸ Paediatric Neurosurgery, Great Ormond Street Hospital, London, UK
⁹ Paediatric Neurosurgery, University Hospitals Bristol NHS Trust, Bristol, UK
^* Corresponding author Email: Karen.Luyt@bristol.ac.uk

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