Triple versus guideline antiplatelet therapy to prevent recurrence after acute ischaemic stroke or transient ischaemic attack: the TARDIS RCT

Bath, Philip M; Woodhouse, Lisa J; Appleton, Jason P; Beridze, Maia; Christensen, Hanne; Dineen, Robert A; Flaherty, Katie; Duley, Lelia; England, Timothy J; Havard, Diane; Heptinstall, Stan; James, Marilyn; Kasonde, Chibeka; Krishnan, Kailash; Markus, Hugh S; Montgomery, Alan A; Pocock, Stuart; Randall, Marc; Ranta, Annamarei; Robinson, Thompson G; Scutt, Polly; Venables, Graham S; Sprigg, Nikola

doi:10.3310/hta22480

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The incidence and severity of recurrent stroke or transient ischaemic attack did not differ between triple and guideline therapy.

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Philip M Bath ^1,^2,^*, Lisa J Woodhouse ¹, Jason P Appleton ^1,², Maia Beridze ³, Hanne Christensen ⁴, Robert A Dineen ⁵, Katie Flaherty ¹, Lelia Duley ⁶, Timothy J England ⁷, Diane Havard ¹, Stan Heptinstall ¹, Marilyn James ⁸, Chibeka Kasonde ⁹, Kailash Krishnan ^1,², Hugh S Markus ¹⁰, Alan A Montgomery ⁶, Stuart Pocock ¹¹, Marc Randall ¹², Annamarei Ranta ¹³, Thompson G Robinson ¹⁴, Polly Scutt ¹, Graham S Venables ¹⁵, Nikola Sprigg ^1,²

¹ Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK
² Stroke, Nottingham University Hospitals NHS Trust, Nottingham, UK
³ Department of Neurology, Hospital of War Veterans, Tbilisi, Georgia
⁴ Department of Neurology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
⁵ Radiological Sciences, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK
⁶ Nottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK
⁷ Vascular Medicine, Division of Medical Sciences and Graduate Entry Medicine, University of Nottingham, Nottingham, UK
⁸ Health Economics, Division of Rehabilitation and Ageing, University of Nottingham, Nottingham, UK
⁹ Lowdham Medical Centre, Nottingham, UK
¹⁰ Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
¹¹ Medical Statistics Unit, London School of Hygiene & Tropical Medicine, London, UK
¹² Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
¹³ Department of Neurology, Wellington Hospital and University of Otago, Wellington, New Zealand
¹⁴ Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
¹⁵ Department of Neurology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
^* Corresponding author Email: philip.bath@nottingham.ac.uk

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