The feasibility of early pulmonary rehabilitation and activity after COPD exacerbations: external pilot randomised controlled trial, qualitative case study and exploratory economic evaluation

Cox, Matthew; O’Connor, Catherine; Biggs, Katie; Hind, Daniel; Bortolami, Oscar; Franklin, Matthew; Collins, Barbara; Walters, Stephen; Wailoo, Allan; Channell, Julie; Albert, Paul; Freeman, Ursula; Bourke, Stephen; Steiner, Michael; Miles, Jon; O’Brien, Tom; McWilliams, David; Schofield, Terry; O’Reilly, John; Hughes, Rodney

doi:10.3310/hta22110

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Early pulmonary rehabilitation was difficult to recruit to and deliver in hospitals compared to home-based sessions so a full RCT would not be feasible, although data collected may inform future trial design.

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Matthew Cox ¹, Catherine O’Connor ¹, Katie Biggs ^2,^*, Daniel Hind ², Oscar Bortolami ², Matthew Franklin ³, Barbara Collins ⁴, Stephen Walters ², Allan Wailoo ³, Julie Channell ⁵, Paul Albert ⁵, Ursula Freeman ¹, Stephen Bourke ⁶, Michael Steiner ⁷, Jon Miles ⁸, Tom O’Brien ¹, David McWilliams ⁹, Terry Schofield ¹, John O’Reilly ⁵, Rodney Hughes ¹

¹ Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
² Design, Trials and Statistics (DTS), School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
³ Health Economics and Decision Science (HEDS), School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
⁴ Simbiotic Consulting Limited, Glasgow, UK
⁵ Aintree University Hospital NHS Foundation Trust, Liverpool, UK
⁶ Northumbria Healthcare NHS Foundation Trust, Newcastle upon Tyne, UK
⁷ University Hospitals of Leicester NHS Trust, Leicester, UK
⁸ Rotherham NHS Foundation Trust, Rotherham, UK
⁹ University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
^* Corresponding author Email: c.e.biggs@sheffield.ac.uk

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