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Study found that leukotriene antagonists are unlikely to be a cost-effective alternative to inhaled corticosteroids, at 2005 prices, as initial asthma controller therapy at step 2 of the British Thoracic Society (BTS) guidelines, but evidence suggests that they are clinically equivalent to long-acting β2-agonists (LABAs) as add-on to inhaled corticosteroids in terms of quality of life as well as secondary measures; furthermore, they could be an alternative to LABAs at step 3 of the BTS guidelines
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D Price, S Musgrave, E Wilson, E Sims, L Shepstone, A Blyth, J Murdoch, M Mugford, E Juniper, J Ayres, S Wolfe, D Freeman, A Lipp, R Gilbert & I Harvey.
D Price 1,*, S Musgrave 2, E Wilson 2, E Sims 2, L Shepstone 2, A Blyth 2, J Murdoch 3, M Mugford 2, E Juniper 4, J Ayres 5, S Wolfe 6, D Freeman 7, A Lipp 8, R Gilbert 9, I Harvey 2
1 Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK
2 Norwich Medical School, University of East Anglia, Norwich, UK
3 School of Nursing and Midwifery, University of East Anglia, Norwich, UK
4 Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
5 School of Health & Population Sciences, University of Birmingham, Birmingham, UK
6 Thorpewood GP Surgery, Norwich, UK
7 Sheringham Medical Practice, Norfolk, UK
8 Great Yarmouth and Waveney Primary Care Trust, Norfolk, UK
9 Castle GP Partnership, Norwich, UK
* Corresponding author Email: david@respiratoryresearch.org
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