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Daily injections of anakinra did not show change in disease activity compared with placebo when assessed by the Palmoplantar Pustulosis Area and Severity Index at 8 weeks.
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Suzie Cro
[Image - ORCID logo], Victoria Cornelius
[Image - ORCID logo], Francesca Capon
[Image - ORCID logo], Jonathan Barker
[Image - ORCID logo], David Burden
[Image - ORCID logo], Christopher Griffiths
[Image - ORCID logo], Helen Jane Lachmann
[Image - ORCID logo], Helen McAteer
[Image - ORCID logo], Prakash Patel
[Image - ORCID logo], Andrew Pink
[Image - ORCID logo], Nick Reynolds
[Image - ORCID logo], Richard Warren
[Image - ORCID logo] & Catherine Smith
[Image - ORCID logo].
Suzie Cro 1, Victoria Cornelius 1, Francesca Capon 2, Jonathan Barker 3, David Burden 4, Christopher Griffiths 5,6, Helen Jane Lachmann 7, Helen McAteer 8, Prakash Patel 9, Andrew Pink 9, Nick Reynolds 10,11,12, Richard Warren 5,6,13, Catherine Smith 9,*
1 Imperial Clinical Trials Unit, Imperial College London, London, UK
2 Department of Medical & Molecular Genetics, King’s College London, London, UK
3 St John’s Institute of Dermatology, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King’s College London, London, UK
4 Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UK
5 Manchester Centre for Dermatology Research, University of Manchester, Manchester, UK
6 Salford Royal NHS Foundation Trust, Manchester, UK
7 The National Amyloidosis Centre, University College London, London, UK
8 The Psoriasis Association, Northampton, UK
9 St John’s Institute of Dermatology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
10 Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
11 Department of Dermatology, Royal Victoria Infirmary, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
12 National Institute for Health Research Newcastle Biomedical Research Centre, Newcastle Hospitals NHS Foundation Trust and Newcastle University, Newcastle upon Tyne, UK
13 Manchester National Institute for Health Research Biomedical Research Centre, Manchester, UK
* Corresponding author Email: catherine.smith@kcl.ac.uk
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