Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding: the UCON randomised controlled trial and mechanism of action study

Whitaker, Lucy HR; Middleton, Lee J; Priest, Lee; Odedra, Smita; Cheed, Versha; Nicholls, Elaine P; Williams, Alistair RW; Roberts, Neil; Stubbs, Clive E; Tryposkiadis, Konstantios; Bensoussane, Hannah; Chodankar, Rohan; Murray, Alison A; Nicol, Moira; Tsolova, Aleksandra O; Yin, Kaiming; Cruz, Marcos; Leow, Hui Wei; Kershaw, Lucy E; McLenachan, Suzanne L; McKillop, Graham; Walker, Jane; Semple, Scott I; Clark, T Justin; Lumsden, Mary Ann; Hapangama, Dharani K; Saraswat, Lucky; Bhattacharya, Siladitya; Smith, Paul; Daniels, Jane; Critchley, Hilary OD

doi:10.3310/FGLQ1687

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Lucy HR Whitaker ¹, Lee J Middleton ², Lee Priest ², Smita Odedra ², Versha Cheed ², Elaine P Nicholls ³, Alistair RW Williams ⁴, Neil Roberts ¹, Clive E Stubbs ², Konstantios Tryposkiadis ², Hannah Bensoussane ², Rohan Chodankar ¹, Alison A Murray ¹, Moira Nicol ¹, Aleksandra O Tsolova ¹, Kaiming Yin ¹, Marcos Cruz ⁵, Hui Wei Leow ¹, Lucy E Kershaw ⁶, Suzanne L McLenachan ⁷, Graham McKillop ⁷, Jane Walker ⁸, Scott I Semple ⁶, T Justin Clark ⁹, Mary Ann Lumsden ¹⁰, Dharani K Hapangama ¹¹, Lucky Saraswat ¹², Siladitya Bhattacharya ¹², Paul Smith ¹³, Jane Daniels ¹⁴, Hilary OD Critchley ^1,^*

¹ MRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, UK
² Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK
³ Adcal H.R. Consultancy, ,
⁴ Division of Pathology, University of Edinburgh, Edinburgh, UK
⁵ Department of Mathematics, Statistics and Computer Science, University of Cantabria, , Spain
⁶ Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
⁷ Department of Clinical Radiology, Royal Infirmary of Edinburgh, Edinburgh, UK
⁸ Simpson Centre for Reproductive Health, Royal Infirmary, Edinburgh, UK
⁹ Birmingham Women’s and Children’s Hospital, Birmingham, UK
¹⁰ Reproductive and Maternal Medicine, University of Glasgow, Glasgow, UK
¹¹ Department of Women’s and Children’s Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK
¹² University of Aberdeen, Aberdeen, UK
¹³ University of Birmingham, Birmingham, UK
¹⁴ Nottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK
^* Corresponding author Email: hilary.critchley@ed.ac.uk

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