Liver resection surgery compared with thermal ablation in high surgical risk patients with colorectal liver metastases: the LAVA international RCT

Davidson, Brian; Gurusamy, Kurinchi; Corrigan, Neil; Croft, Julie; Ruddock, Sharon; Pullan, Alison; Brown, Julia; Twiddy, Maureen; Birtwistle, Jaqueline; Morris, Stephen; Woodward, Nick; Bandula, Steve; Hochhauser, Daniel; Prasad, Raj; Olde Damink, Steven; Coolson, Marielle; Laarhoven, K van; de Wilt, Johannes HW

doi:10.3310/hta24210

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Only nine participants were randomised so recruitment feasibility was not demonstrated during the pilot stage of the trial; therefore, the trial closed early.

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Brian Davidson ^1,^*, Kurinchi Gurusamy ¹, Neil Corrigan ², Julie Croft ², Sharon Ruddock ², Alison Pullan ², Julia Brown ², Maureen Twiddy ^3,⁴, Jaqueline Birtwistle ³, Stephen Morris ⁵, Nick Woodward ⁶, Steve Bandula ⁷, Daniel Hochhauser ⁸, Raj Prasad ⁹, Steven Olde Damink ¹⁰, Marielle Coolson ¹⁰, K van Laarhoven ¹¹, Johannes HW de Wilt ¹¹

¹ Royal Free Campus, Division of Surgery and Interventional Science, University College London, London, UK
² Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK
³ Leeds Institute of Health Sciences, University of Leeds, Leeds, UK
⁴ Institute of Clinical and Applied Health Research, Faculty of Health Science, University of Hull, Hull, UK
⁵ Department of Applied Health Research, University College London, London, UK
⁶ Radiology, Royal Free Hospital, London, UK
⁷ Radiology, University College Hospital, London, UK
⁸ Cancer Institute, University College London, London, UK
⁹ Surgery and Transplantation, Leeds Teaching Hospital, Leeds, UK
¹⁰ General Surgery, Maastricht University, Maastricht, the Netherlands
¹¹ Surgery, Radboud University Medical Centre, Nijmegen, the Netherlands
^* Corresponding author Email: b.davidson@ucl.ac.uk

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