An intervention to support adherence to inhaled medication in adults with cystic fibrosis: the ACtiF research programme including RCT

Wildman, Martin J; O’Cathain, Alicia; Hind, Daniel; Maguire, Chin; Arden, Madelynne A; Hutchings, Marlene; Bradley, Judy; Walters, Stephen J; Whelan, Pauline; Ainsworth, John; Tappenden, Paul; Buchan, Iain; Elliott, Rachel; Nicholl, Jon; Elborn, Stuart; Michie, Susan; Mandefield, Laura; Sutton, Laura; Hoo, Zhe Hui; Drabble, Sarah J; Lumley, Elizabeth; Beever, Daniel; Navega Biz, Aline; Scott, Anne; Waterhouse, Simon; Robinson, Louisa; Hernández Alava, Mónica; Sasso, Alessandro

doi:10.3310/pgfar09110

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This research programme developed a feasible and acceptable intervention that increased adherence to inhaled medication but did not reduce pulmonary exacerbation rates at 12 months.

Martin J Wildman , Alicia O’Cathain , Daniel Hind , Chin Maguire , Madelynne A Arden , Marlene Hutchings , Judy Bradley , Stephen J Walters , Pauline Whelan , John Ainsworth , Paul Tappenden , Iain Buchan , Rachel Elliott , Jon Nicholl , Stuart Elborn , Susan Michie , Laura Mandefield , Laura Sutton , Zhe Hui Hoo , Sarah J Drabble , Elizabeth Lumley , Daniel Beever , Aline Navega Biz , Anne Scott , Simon Waterhouse , Louisa Robinson , Mónica Hernández Alava & Alessandro Sasso .

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Martin J Wildman ^1,², Alicia O’Cathain ^2,^*, Daniel Hind ³, Chin Maguire ³, Madelynne A Arden ⁴, Marlene Hutchings ¹, Judy Bradley ⁵, Stephen J Walters ², Pauline Whelan ⁶, John Ainsworth ⁶, Paul Tappenden ², Iain Buchan ^6,⁷, Rachel Elliott ⁸, Jon Nicholl ², Stuart Elborn ⁵, Susan Michie ⁹, Laura Mandefield ², Laura Sutton ², Zhe Hui Hoo ^1,², Sarah J Drabble ², Elizabeth Lumley ², Daniel Beever ³, Aline Navega Biz ², Anne Scott ³, Simon Waterhouse ³, Louisa Robinson ³, Mónica Hernández Alava ², Alessandro Sasso ²

¹ Sheffield Adult Cystic Fibrosis Centre, Northern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
² School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
³ Clinical Trials Research Unit, University of Sheffield, Sheffield, UK
⁴ Centre for Behavioural Science and Applied Psychology, Sheffield Hallam University, Sheffield, UK
⁵ Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, UK
⁶ Health eResearch Centre, Division of Imaging, Informatics and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
⁷ Department of Public Health and Policy, Institute of Population Health Sciences, University of Liverpool, Liverpool, UK
⁸ Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
⁹ Centre for Behaviour Change, University College London, London, UK
^* Corresponding author Email: a.ocathain@sheffield.ac.uk

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