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This study concluded that prehospital use of CPAP for Acute Respiratory Failure was not feasible for a full trial largely because it seems unlikely to materially reduce mortality.

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Gordon W Fuller 1,*, Samuel Keating 2, Steve Goodacre 1, Esther Herbert 2, Gavin D Perkins 3, Andy Rosser 4, Imogen Gunson 4, Joshua Miller 4, Matthew Ward 4, Mike Bradburn 2, Praveen Thokala 5, Tim Harris 6, Margaret M Marsh 7, Alexander J Scott 2, Cindy Cooper 2

1 Centre for Urgent and Emergency Care Research, School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
2 Clinical Trials Research Unit, School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
3 Warwick Clinical Trials Unit, University of Warwick, Coventry, UK
4 West Midlands Ambulance Service, Brierley Hill, UK
5 Health Economics and Decision Science, School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
6 Centre for Neuroscience and Trauma, Blizard Institute, Queen Mary University of London, London, UK
7 Sheffield Emergency Care Forum, Royal Hallamshire Hospital, Sheffield, UK
* Corresponding author Email: g.fuller@sheffield.ac.uk

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