LIFELAX - diet and LIFEstyle versus LAXatives in the management of chronic constipation in older people: randomised controlled trial

Speed, C; Heaven, B; Adamson, A; Bond, J; Corbett, S; Lake, AA; May, C; Vanoli, A; McMeekin, P; Moynihan, P; Rubin, G; Steen, IN; McColl, E

doi:10.3310/hta14520

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Due to the low number of participants in this trial, no firm conclusions could be drawn about the effectiveness of the interventions. However, a number of factors that contributed to the premature closure of the trial are highlighted, which may be relevant to others conducting research on a similar topic or population

C Speed, B Heaven, A Adamson, J Bond, S Corbett, AA Lake, C May, A Vanoli, P McMeekin, P Moynihan, G Rubin, IN Steen & E McColl.

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C Speed ¹, B Heaven ², A Adamson ^2,³, J Bond ^1,⁴, S Corbett ⁵, AA Lake ^2,³, C May ², A Vanoli ², P McMeekin ², P Moynihan ^3,^4,⁶, G Rubin ^7,⁸, IN Steen ², E McColl ^1,^*

¹ Newcastle Clinical Trials Unit, Institute of Health and Society, Newcastle University, Newcastle, UK
² Institute of Health and Society, Newcastle University, Newcastle, UK
³ Human Nutrition Research Centre, Newcastle University, Newcastle, UK
⁴ Institute for Ageing and Health, Newcastle University, Newcastle, UK
⁵ North Tyneside General Hospital, Northumbria Healthcare Trust, North Shields, UK
⁶ Dental School, Newcastle University, Newcastle, UK
⁷ Department of Primary Care, University of Sunderland, Sunderland, UK
⁸ Northern & Yorkshire Primary Care Research Network, Stockton-on-Tees, UK
^* Corresponding author Email: e.mccoll@ncl.ac.uk

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