Journals Library


HTA - 10/34/01

OPTIMA prelim: Optimal Personalised Treatment of early breast cancer using Multi-parameter analysis: preliminary study

Project title: OPTIMA prelim: Optimal Personalised Treatment of early breast cancer using Multi-parameter analysis: preliminary study

Call to action: 10/34 The clinical and cost effectiveness of personalised care in the treatment of women with breast cancer

Research type: Primary Research

Chief investigator: Professor Robert SteinORCID logo https://orcid.org/0000-0003-2969-0415

Lead Author: Professor Robert Stein

Contractor: University College London

Cost: £1,959,668.00

Co-investigators: Dr Adrienne Morgan, Dr Andreas Makris, Dr Daniel Rea, Dr Elena Provenzano, Dr Helena Earl, Dr Louise Hiller, Dr Luke Hughes-Davies, Dr Peter Canney, Dr Peter Hall, Professor Adele Francis, Professor Christopher McCabe, Professor Christopher Poole, Professor David Cameron, Professor Janet Dunn, Professor Jenny Donovan, Professor John Bartlett, Professor Nigel Stallard, Professor Sarah Pinder.

Started: May 2012 | Status: Published February 2016

ISRCTN: 42400492

The study found that a large-scale study of multiparameter test-directed chemotherapy allocation in a high-risk population of patients with oestrogen receptor (ER)-positive, human epidermal growth factor 2 (HER2)-negative cancer is feasible in the UK. Health economics modelling showed the value of information to the NHS from further research into multiparameter testing is high irrespective of the test evaluated.

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