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HTA - 10/34/01
OPTIMA prelim: Optimal Personalised Treatment of early breast cancer using Multi-parameter analysis: preliminary study
Project title: OPTIMA prelim: Optimal Personalised Treatment of early breast cancer using Multi-parameter analysis: preliminary study
Research type: Primary Research
Lead Author: Professor Robert Stein
Contractor: University College London
Co-investigators: Dr Adrienne Morgan, Dr Andreas Makris, Dr Daniel Rea, Dr Elena Provenzano, Dr Helena Earl, Dr Louise Hiller, Dr Luke Hughes-Davies, Dr Peter Canney, Dr Peter Hall, Professor Adele Francis, Professor Christopher McCabe, Professor Christopher Poole, Professor David Cameron, Professor Janet Dunn, Professor Jenny Donovan, Professor John Bartlett, Professor Nigel Stallard, Professor Sarah Pinder.
Started: May 2012 | Status: Published February 2016
The study found that a large-scale study of multiparameter test-directed chemotherapy allocation in a high-risk population of patients with oestrogen receptor (ER)-positive, human epidermal growth factor 2 (HER2)-negative cancer is feasible in the UK. Health economics modelling showed the value of information to the NHS from further research into multiparameter testing is high irrespective of the test evaluated.
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