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HTA - 17/34/01

A parallel group, double-blind, randomised, placebo-controlled trial comparing the effectiveness and cost-consequence and cost effectiveness of low dose oral modified release morphine (MRM) versus placebo on the intensity of worst breathlessness in people with chronic breathlessness.

Project title: A parallel group, double-blind, randomised, placebo-controlled trial comparing the effectiveness and cost-consequence and cost effectiveness of low dose oral modified release morphine (MRM) versus placebo on the intensity of worst breathlessness in people with chronic breathlessness.

Call to action: 17/34 17/34 Opioids for the treatment of breathlessness in palliative care

Research type: Primary Research

Chief investigator: Professor Miriam JohnsonORCID logoorcid.org/0000-0001-6204-9158

Contractor: Hull and East Yorkshire Hospitals NHS Trust

Cost: £1,231,254.61

Co-investigators: Dr Deans Buchanan, Dr Jeremy Keen, Dr Julie Seymour, Dr Mark Pearson, Dr Nazia Chaudhuri, Dr Peter Hall, Dr Sabrina Bajwah, Dr Simon Hart, Professor David Currow, Professor Irene Higginson, Professor John Norrie, Professor Marie Fallon.

Started: March 2019 | Status: Research in progress

ISRCTN: 87329095

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