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HTA - 15/80/40
Risk-benefit and costs of unicompartmental (compared to total) knee replacement for patients with multiple co-morbidities: a non-randomised study, and different novel approaches to minimise confounding.
Project title: Risk-benefit and costs of unicompartmental (compared to total) knee replacement for patients with multiple co-morbidities: a non-randomised study, and different novel approaches to minimise confounding.
Call to action: 15/80 15/80 HTA Efficient Study Designs
Research type: Primary Research
Chief investigator: Professor Daniel Prieto-Alhambra
Lead Author: Professor Daniel Prieto-Alhambra
Contractor: University of Oxford
Co-investigators: Associate Professor Rafael Pinedo-Villanueva, Ms Susan Thwaite, Professor Alan Silman, Professor Andrew Carr, Professor Andrew Judge, Professor David Beard, Professor David Murray, Professor Ian Douglas, Professor Irene Petersen, Professor Jeremy Wilkinson, Professor Jose M Valderas, Professor Nigel Arden, Professor Sarah Lamb.
Started: June 2017 | Status: Published November 2021
This study confirmed the results of the TOPKAT study and unicompartmental knee replacement was safer and less expensive than total knee replacement for patients with severe comorbidity.
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