Journals Library


HTA - 14/210/07

Prognostic biomarkers to identify patients with severe Crohn's disease: Systematic review, meta-analysis and prognostic model with external validation.

Project title: Prognostic biomarkers to identify patients with severe Crohn's disease: Systematic review, meta-analysis and prognostic model with external validation.

Call to action: 14/210 14/210 Prognostic markers in early Crohn's Disease

Research type: Evidence Synthesis

Chief investigator: Professor Steve HalliganORCID logo

Lead Author: Professor Steve HalliganORCID logo

Contractor: University College London

Cost: £231,378.98

Co-investigators: Dr Manuel Rodriguez-JustoORCID logo, Dr Stuart BloomORCID logo, Dr Tariq AhmadORCID logo, Mr Ilan JacobsORCID logo, Professor Stuart TaylorORCID logo, Professor Susan MallettORCID logo.

Started: April 2016 | Status: Published July 2021

PROSPERO registration: CRD42016029363

This review found limited prognostic evidence for most individual biomarkers but identified eight with potential predictor capability for severe Crohn's disease.

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