Journals Library


HTA - 13/115/48

Antidepressants to prevent relapse in depression

Project title: Antidepressants to prevent relapse in depression

Call to action: 14/08 14/08 HTA CET Open Call, Outline to Full Form

Research type: Primary Research

Chief investigator: Professor Glyn LewisORCID logo

Lead Author: Ms Larisa DuffyORCID logo

Contractor: University College London

Cost: £1,807,618.00

Co-investigators: Dr Rachael HunterORCID logo, Professor Anthony KendrickORCID logo, Professor David KesslerORCID logo, Professor Irwin NazarethORCID logo, Professor Michael KingORCID logo, Professor Michael MooreORCID logo, Professor Nick FreemantleORCID logo, Professor Nicola WilesORCID logo, Professor Simon GilbodyORCID logo.

Started: May 2016 | Status: Published November 2021

ISRCTN: 15969819

This trial showed patients who discontinue long-term maintenance antidepressants are at increased risk of relapse and withdrawal symptoms, however, a substantial proportion of patients can discontinue antidepressants without relapse.

Links to project documentation

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Background & Research Questions

Why the research is being done and what is being asked

Methods

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Publications & Outputs

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Outcomes & Impact

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