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HTA - 13/115/48
Antidepressants to prevent relapse in depression
Project title: Antidepressants to prevent relapse in depression
Call to action: 14/08 14/08 HTA CET Open Call, Outline to Full Form
Research type: Primary Research
Chief investigator: Professor Glyn Lewis
Lead Author: Ms Larisa Duffy
Contractor: University College London
Co-investigators: Dr Rachael Hunter, Professor Anthony Kendrick, Professor David Kessler, Professor Irwin Nazareth, Professor Michael King, Professor Michael Moore, Professor Nick Freemantle, Professor Nicola Wiles, Professor Simon Gilbody.
Started: May 2016 | Status: Published November 2021
This trial showed patients who discontinue long-term maintenance antidepressants are at increased risk of relapse and withdrawal symptoms, however, a substantial proportion of patients can discontinue antidepressants without relapse.
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