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HTA - 12/33/28

A multi-centre, randomised, double blind, placebo-controlled, parallel group trial of the effectiveness of the nocturnal use of a Temperature Controlled Laminar Airflow (TLA) Device (Airsonett®) in adults with poorly-controlled, severe allergic asthma: the LASER trial

Project title: A multi-centre, randomised, double blind, placebo-controlled, parallel group trial of the effectiveness of the nocturnal use of a Temperature Controlled Laminar Airflow (TLA) Device (Airsonett®) in adults with poorly-controlled, severe allergic asthma: the LASER trial

Call to action: 12/33 12/33 HTA CET Open Call

Research type: Primary Research

Chief investigator: Professor Anoop ChauhanORCID logoorcid.org/0000-0003-4044-6114

Lead Author: Dr Melissa KapoorORCID logoorcid.org/0000-0002-1811-2401

Contractor: Portsmouth Hospitals NHS Trust

Cost: £1,258,857.34

Co-investigators: Dr Adel Mansur, Dr Ann Dewey, Dr Ly-Mee Yu, Dr Ramon Luengo-Fernandez, Dr Thomas Brown, Mr Keith Boughton, Ms Carole Fogg, Ms Emma Munro, Professor Najib Rahman, Professor Peter Bradding, Professor Peter Howarth, Professor Taraneh Dean.

Started: December 2013 | Status: Published June 2019

ISRCTN: 46346208

The active device did not reduce the frequency of severe asthma exacerbations more than the placebo.

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