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HTA - 12/201/02

A randomised controlled trial of adalimumab injection compared with placebo injection for patients receiving physiotherapy treatment for sciatica. Trial acronym: Sub-Cutaneous Injection of Adalimumab Trial compared with Control (SCIATiC)

Project title: A randomised controlled trial of adalimumab injection compared with placebo injection for patients receiving physiotherapy treatment for sciatica. Trial acronym: Sub-Cutaneous Injection of Adalimumab Trial compared with Control (SCIATiC)

Call to action: 12/201 12/201 Management of sciatica (lumbosacral radiculopathy) and suspected sciatica

Research type: Primary Research

Chief investigator: Professor Nefyn WilliamsORCID logoorcid.org/0000-0002-8078-409X

Lead Author: Professor Nefyn Williams

Contractor: Bangor University

Cost: £532,368.40

Co-investigators: Dr Dawn Carnes, Dr Kika Konstantinou, Dr Stephane Genevay, Dr Valerie Sparkes, Dr Zoe Hoare, Ms Jackie McCarthy, Professor Clare Wilkinson, Professor David Walsh, Professor Dyfrig Hughes, Professor Dylan Morrissey, Professor Elaine Hay, Professor John Isaacs, Professor Nadine Foster.

Started: January 2015 | Status: Published October 2017

ISRCTN: 14569274

This trial closed because the internal pilot study was discontinued due to low recruitment after eight participants were recruited from two out of six sites.

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