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HTA - 12/127/134

A pragmatic randomised controlled trial of intravenous levetiracetam versus intravenous phenytoin in terminating acute, prolonged tonic clonic seizures including convulsive status epilepticus in children, the 'EcLiPSE' Study: Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus.

Project title: A pragmatic randomised controlled trial of intravenous levetiracetam versus intravenous phenytoin in terminating acute, prolonged tonic clonic seizures including convulsive status epilepticus in children, the 'EcLiPSE' Study: Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus.

Call to action: 12/127 12/127 HTA CET Open Call, Outline Form

Research type: Primary Research

Chief investigator: Dr Richard Appleton

Contractor: Alder Hey Children's NHS Foundation Trust

Cost: £1,515,580.00

Co-investigators: Dr Anand Iyer, Dr Kerry Woolfall, Dr Mark Lyttle, Dr Mary Ryan, Dr Shrouk Messahel, Miss Helen Hickey, Mrs Heather Bagley, Mrs Victoria Evans, Ms Jo Noblet, Professor Carrol Gamble.

Started: June 2014 | Status: Research in progress

ISRCTN: 22567894

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