Journals Library


HTA - 11/129/187

Human papillomavirus infection: a randomised controlled trial of Imiquimod versus Podophyllotoxin, in combination with quadrivalent human papillomavirus vaccination in the treatment and prevention of recurrence of anogenital warts (HIPvac Trial)

Project title: Human papillomavirus infection: a randomised controlled trial of Imiquimod versus Podophyllotoxin, in combination with quadrivalent human papillomavirus vaccination in the treatment and prevention of recurrence of anogenital warts (HIPvac Trial)

Call to action: 11/129 Rapid trials to inform clinical decision making in the NHS

Research type: Primary Research

Chief investigator: Dr Richard GilsonORCID logo

Lead Author: Dr Richard GilsonORCID logo

Contractor: University College London

Cost: £1,233,564.93

Co-investigators: Dr Kate SoldanORCID logo, Dr Lewis HaddowORCID logo, Dr Mayura NathanORCID logo, Miss Michelle Tetlow, Professor Andrew CopasORCID logo, Professor Caroline DoreORCID logo, Professor Charles LaceyORCID logo, Professor Mark JitORCID logo.

Started: September 2013 | Status: Published September 2020

ISRCTN: 32729817

Wart clearance and recurrence were similar with either topical treatment and, though a benefit of vaccine was not demonstrated in this study, further research appears justified.

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