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HTA - 11/129/148
A multicentre randomiSed controlled TRial of IntraVEnous Immunoglobulin (IVIg) versus standard therapy for the treatment of transverse myelitis in adults and children (STRIVE trial)
Project title: A multicentre randomiSed controlled TRial of IntraVEnous Immunoglobulin (IVIg) versus standard therapy for the treatment of transverse myelitis in adults and children (STRIVE trial)
Call to action: 11/129 Rapid trials to inform clinical decision making in the NHS
Research type: Primary Research
Contractor: Guy's and St Thomas' NHS Foundation Trust
Co-investigators: Dr Anu Jacob, Dr Jacqueline Palace, Dr Michael Absoud, Dr Mike Pike, Dr Peter Brex, Ms Caroline Murphy, Ms Jennifer Hellier, Ms Joanna Kelly, Professor Andrew Pickles, Professor Gavin Giovannoni, Professor Neil Robertson, Professor Olga Ciccarelli, Professor Paul McCrone.
Started: June 2014 | Status: Published May 2017
The study only randomised two patients and so could not address the benefits of intravenous immunoglobulin, however they identified several recruitment barriers which would need to be overcome in future trials.
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