Journals Library


HTA - 11/129/148

A multicentre randomiSed controlled TRial of IntraVEnous Immunoglobulin (IVIg) versus standard therapy for the treatment of transverse myelitis in adults and children (STRIVE trial)

Project title: A multicentre randomiSed controlled TRial of IntraVEnous Immunoglobulin (IVIg) versus standard therapy for the treatment of transverse myelitis in adults and children (STRIVE trial)

Call to action: 11/129 Rapid trials to inform clinical decision making in the NHS

Research type: Primary Research

Chief investigator: Dr Ming LimORCID logoorcid.org/0000-0001-7738-8910

Lead Author: Dr Michael AbsoudORCID logoorcid.org/0000-0002-0577-1897

Contractor: Guy's and St Thomas' NHS Foundation Trust

Cost: £323,292.27

Co-investigators: Dr Anu Jacob, Dr Jacqueline Palace, Dr Michael Absoud, Dr Mike Pike, Dr Peter Brex, Ms Caroline Murphy, Ms Jennifer Hellier, Ms Joanna Kelly, Professor Andrew Pickles, Professor Gavin Giovannoni, Professor Neil Robertson, Professor Olga Ciccarelli, Professor Paul McCrone.

Started: June 2014 | Status: Published May 2017

ISRCTN: 12127581

The study only randomised two patients and so could not address the benefits of intravenous immunoglobulin, however they identified several recruitment barriers which would need to be overcome in future trials.

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