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HTA - 10/57/20

A randomised controlled trial of standard-of-care wound management versus negative pressure wound therapy in the treatment of adult patients with an open fracture of the lower limb

Project title: A randomised controlled trial of standard-of-care wound management versus negative pressure wound therapy in the treatment of adult patients with an open fracture of the lower limb

Call to action: 10/57 HTA Clinical Trials - January 2011 Board submission (July 2010 deadline)

Research type: Primary Research

Chief investigator: Professor Matthew CostaORCID logoorcid.org/0000-0003-3644-1388

Lead Author: Professor Matthew CostaORCID logoorcid.org/0000-0003-3644-1388

Contractor: University Hospitals Coventry & Warwickshire NHS Trust

Cost: £2,047,962.49

Co-investigators: Dr Elizabeth Tutton, Dr Juul Achten, Professor Damian Griffin, Professor Julie Bruce, Professor Keith Willett, Professor Sarah Lamb, Professor Simon Gates, Professor Stavros Petrou, Professor Steven Jeffery.

Started: April 2012 | Status: Published December 2018

ISRCTN: 33756652

There was no evidence that negative pressure wound therapy improves outcomes after 12 months for adults with open fracture of the lower limb.

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