Journals Library


HTA - 07/29/01

Development and validation of a risk model for identification of non-neutropenic, critically-ill, adult patients at high risk of invasive candida infection

Project title: Development and validation of a risk model for identification of non-neutropenic, critically-ill, adult patients at high risk of invasive candida infection

Call to action: 07/29 Antifungal agents for preventing fungal infections in non-neutropenic critically ill patients

Research type: Primary Research

Chief investigator: Professor David HarrisonORCID logoorcid.org/0000-0002-9002-9098

Lead Author: Professor David HarrisonORCID logoorcid.org/0000-0002-9002-9098

Contractor: Intensive Care National Audit & Research Centre

Cost: £737,880.00

Co-investigators: Dr Neil Soni, Professor Christopher Kibbler, Professor Jonathan Edgeworth, Professor Kathryn Rowan, Professor Mark Jit, Professor Richard Grieve, Professor Rosemary Barnes.

Started: November 2008 | Status: Published February 2013

Study found that there was a low incidence of invasive fungal disease (IFD) among non-neutropenic critically ill adult patients. Risk modelling produced simple risk models that provided acceptable discrimination for identifying patients at 'high risk' of invasive Candida infection. The economic model suggested that a strategy of no risk assessment and no antifungal prophylaxis was most cost-effective.

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